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Scar tissue is primarily composed of disordered bundles of collagen as the skins primary concern is to repair damaged skin as quickly as possible and is less concerned with appearance

Diagnosis of Hashimoto thyroiditis is done by ultrasound, thyroid function testing, and antibody detection

Among the numerous partners that interact with NRF2 regulating its activity, two members of the CNC-bZIP protein family BTB and CNC homolog 1 (BACH1) and BTB and CNC homolog 2 (BACH2) are two negative regulators of NRF2: they compete with NRF2 for the binding to ARE sequences of target genes, thereby preventing the production of antioxidant enzymes and cellular defense against toxicity [232, 233]

Wilsman et al