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however, a normal rate of glucose production is maintained for only ~1 h from the onset of FCI (Belayev et al., Figure 1 Global Cerebral Ischemia GCI results from transient cardiac arrest causing a systemic and complete cessation of blood flow in the whole parenchyma of the brain (Harukuni and Bhardwaj, 2006), which then diminishes the number of neuronal and glial cells and reduces the integrity of the blood-brain barrier (BBB

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