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Peer review Peer review information Nature Communications thanks Jianhua He and the other, anonymous, reviewers for their contribution to the peer review of this work

Levitskaya, N

The neuropsychiatric presentation of Wilsons is the first indication of disease in 4045% of patients older than 20 years of age.2,20 The youngest patient recorded with neurologic onset was 6 years old.2 The symptoms of neurologic involvement of Wilsons are usually related to dysfunction of the basal ganglia, cerebellum, and corticospinal and corticobulbar pathways

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