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Cagrilintide, the second generation (2020s) Novo Nordisk took the Pramlintide concept and applied the same half-life extension strategy that they used with Semaglutide: Kept the proline substitutions (anti-amyloid) Added a C20 fatty diacid via a -Glu linker to a lysine residue, albumin binding Additionally stabilized the N- and C-terminal positions Result: Cagrilintide with a half-life of 6.6 days (vs 50 minutes for Pramlintide)

And we've already had immense success on orthopedic injuries, knees, shoulders, elbows, using traditional MSCs that can't differentiate, right

Like, we've gotten sometimes peptides, and we've had people go from like a 4 to 1 lymphocyte to monocyte ratio to an 8 to 1 ratio

These are unique cells with the ability to morph into any cell type