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2020;22(1):e14725

The composition of aerosols generated by heating e-cigarette liquid is related to the constituents of the liquid ( Even though propylene glycol and vegetable glycerin are included in the Generally Recognized as Safe list by the United States Food and Drug Administration (81) or immunosuppression and cancer promotion meditated by modulation of immune checkpoints ( The main components of e-liquids include propylene glycol, vegetable glycerin, nicotine, and flavoring agents ( Nicotine can modulate the expression of PD-L1, PD-L2, PD-1, CTLA-4, CD47, and CD24 in diseases such as melanoma, lung cancer, breast cancer, and rheumatoid arthritis

E-cigarettes are handheld battery-powered vaporisers, and instead of cigarette smoke, the user inhales vapour