Sikiric et al., 2010, 2011, 2012, 2013, 2014, 2016, 2017, 2018), further studies should explore the relevance of BPC 157, as it increased the survival of cultured enteric neurons and proliferation of cultured EGCs but did not influence the proliferation of cultured enteric glial cells (Wang et al., 2019), which may improve healing of damaged enteric nervous and mucosal structures
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In the phase 2 study published in the New England Journal of Medicine, gastrointestinal symptom rates nearly doubled when participants jumped directly to 8mg instead of titrating gradually from 1mg