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The noble man, Sir Nicot, having procured it to grow in his garden, where it had put forth and multiplied very greatly, was advertised on a day by one of his pages, that a young boy, kinsman of the said page, had laid the said herb (for trials sake), stamped the substance and juice and altogether, upon an ulcer which he had upon his cheek, near unto his nose, next neighbour to a noli me tangere, as having already seized upon the cartilages, and that by the use thereof it was become marvellous well

He was a talk-show host who didnt always seem to enjoy talking to people

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Bibcode:1988PNAS...85.3391C