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In total, 40 male specific- pathogen-free C57BL/6 mice (Hubei Animal Experimental Center) 68 weeks old and weighing 2025 g were housed in the animal experiment center in Renmin Hospital of Wuhan University with 12 h light/dark cycle, temperature of 252C and relative humidity of 5015%

The individual ingredient semaglutide is FDA-approved under the brand names Ozempic and Wegovy, but the compounded triple blend is not an FDA-approved combination product

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This includes, crucially, understanding exactly when and why does GHK-Cu need refrigeration