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As a cytoprotective agent (reviewed [4,5,6]), it may be a suitable form of treatment for pulmonary arterial hypertension, a disease characterized by progressive pulmonary vascular remodeling, resulting in right-side heart failure and premature death in rats given monocrotaline (reviewed [15,16])

Abnormal expression or altered function of glutamate receptors and changes in the subunit composition of the receptors lead to increased sensitivity of neurons to glutamate, prompting the release of more glutamate [16,17,18]

Discussion Although konzo was first described in 1938, the biological mechanisms that contribute to the development of this disease have remained elusive 23

The biggest difference is between topical serums and injectable GHK-Cu