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The aforementioned findings suggest that ferroptosis may be one of the pathogenic mechanisms of PKD, and inhibitors of ferroptosis offer a new perspective for developing treatment strategies for PKD (229)

Despite the multifunctionality of these proteins, GSTs are best known for their ability to transfer the tripeptide gamma-glutamyl-cysteinyl-glycine, also known as glutathione (GSH) to a wide variety of highly genotoxic and cell-damaging molecules, either directly occurred from the extracellular environment or from the intracellular detoxification metabolism

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