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Published animal-model work reported that AOD-9604 produced fat-loss endpoints in obese rodent models without elevating IGF-1, without inducing insulin resistance, and without the cell-proliferation signaling normally associated with the full hGH receptor

Plasma samples were collected in citrate tubes and spun at 2,000 g for 10 min

In some embodiments, any formulation or composition described herein has a pH that allows for sterilization (e.g., by filtration or aseptic mixing or heat treatment and/or autoclaving (e.g., terminal sterilization)) of a formulation or composition without degradation of the therapeutic agent