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The liver stores B12, and these stores can last a significant time (up to several years for non-deficient individuals), but when they are depleted, it takes consistent input to rebuild and maintain them

There are some nerves running through the shoulder and there is always a slight chance a needle may hit a nerve if the injection location is incorrect

Challenges such as safety, dosage optimization, and long-term effects need to be thoroughly addressed before considering 5-Amino-1MQ as a viable anti-aging intervention for humans