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On the other hand, protective bacterial species, such as Bifidobacterium, Lactobacillus and Butyricicoccus, that promote a healthy gut barrier and enhance immune tolerance, are reduced in patients with HT [182]

Although Wilsons disease always begins with liver involvement, many patients may be asymptomatic and therefore go undiagnosed until they present at 2030 years of age with advanced hepatic or neurologic disease

Most of these side effects are mild, but, medical evaluation is recommended to avoid serious side effects and should be treated under supervision

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