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Very common Cytisine side effects include: headaches nausea (feeling sick) vomiting (being sick) diarrhoea constipation weight gain change in appetite (mainly an increase) this is also a common side effect of quitting nicotine, as nicotine is an appetite suppressant dizziness mood changes, including irritability anxiety high blood pressure dry mouth heartburn abdominal pain (especially the upper abdomen) muscle pain rash fatigue sleep disorders (insomnia, drowsiness, lethargy, abnormal dreams, nightmares) increased pulse change in taste Common Cytisine side effects include: slow heart rate difficulty concentrating burning tongue abdominal distention (swelling) malaise (a feeling of discomfort, illness, or unease) Uncommon Cytisine side effects include: feeling of heaviness in the head tiredness sweating decreased libido lacrimation (abnormal or excessive secretion of tears) shortness of breath excessive salivation increased sputum (phlegm) decreased elasticity of the skin an increase in serum transaminase levels shown in blood tests There has been no evidence of serious adverse effects whilst taking Cytisine but like all medications, theres a risk of a severe allergic reaction