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As discussed previously, a tentative example of selective effect would be modulation of S1PR2 in astrocytes, which seems to be linked to glutamate recycling and mitochondrial metabolism (116), both promising mechanisms to ameliorate excitotoxic synaptopathy

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The 17mg/mL in 2 mL vial (34mg total) This mid-size vial offers the same high concentration as the 4 mL version but in a smaller package

In order to collect data electrodes were prepared and filled with a recording solution containing 120 mM K-gluconate, 10 mM KCl2, 5 N-(2,6-dimethyl-phenylcarbamoylmethyl)-triethylammonium bromide, 1mM EGTA, 0.1 mM CaCl2, 2 Mg-ATP, 0.2 tris-GTP, and 10 mM free acid (HEPES)