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The pituitary is connected to the brain, however, so it can get input from a brain area called the hypothalamus

Sublingual tablets and nasal sprays bypass some of the digestive steps, which may be helpful if you have absorption challenges or prefer not to swallow pills. Vitamin B12 injections deliver the vitamin directly into your bloodstream, bypassing the digestive tract and providing faster, more reliable absorption

doi: 10.1016/j.freeradbiomed.2018.12.011 21 SabatierMBirsenRLautureLMoucheSAngelinoPDehairsJet al

Drug metabolism can occur in most cells and organs, but specific organs within the body are considered the primary metabolizing organs (Figure 5.1)