pubmed glutathione system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis New Pub Alert from @UtahCGM!

It reduces pro-inflammatory cytokines such as IL-1, TNF-, and IL-6 while enhancing anti-inflammatory mediators, including IL-10 and CXCL-1, through modulation of NF-B and MAPK signalling (Chuang et al., 2023

These findings indicated that mitochondrial oxidative stress was increased in the Fabry kidney organoids

Additionally, the current study showed that in rats with GN-induced ARF, our treatment regimens, which include solo LS, GSH, and their combination in both NP formulations, significantly reduced serum cystatin C levels and renal tissue concentrations of NGAL and KIM-1, indicating a linked improvement in ARF

We have previously shown that human mast cells synthesize and secrete CRH and express functional CRH receptors (CRH-R1 and CRH-R2) (Kempuraj et al., 2004