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It occurs when the pulp inside a tooth dies

HIV related variables were collected by patient medical chart review and included: nadir and current CD4+ T lymphocyte cell count/mm 3 (CD4), time since HIV diagnosis and cumulative exposure to antiretroviral drugs: protease inhibitors (PIs), nucleoside reverse transcriptase inhibitors (NRTIs) and non-nucleoside reverse transcriptase inhibitors (NNRTIs)