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Remodeling of the interstitial extracellular matrix in white matter multiple sclerosis lesions: Implications for remyelination failure

Dispone inoltre di una solida base di ricerca, con studi che analizzano come la sua struttura modificata resista alla naturale degradazione enzimatica (Ferdinandi et al., 2007, Basic & Clinical Pharmacology)

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In the structure of E-RTC, two nsp13 zinc-binding domains form extensive interactions with two nsp8 N-terminal helices