Current limitations include the complexity of the mechanisms of action, which makes it difficult to identify predictive biomarkers of response, the lack of detailed pharmacokinetic data for synthetic TB-500, and the difficulty of translating effective doses from animal models to humans
Risk is almost always a product of self-sourcing unregulated vials , poor reconstitution , non-sterile technique , or wrong dose for goal - all of which we see in patients who come to us after online DIY protocols
10.1016/j.ajhg.2019.09.006 420 ZhaoX.HuS.WangL.ZhangQ.ZhuX.ZhaoH.et al (2014)
Theres a black market production, primarily in China, that sends large amounts of these peptides to the United States with the label For research only, says Pinchas Cohen, MD, dean and distinguished professor of gerontology, medicine, and biological sciences at the USC Leonard Davis School of Gerontology, who has discovered several investigational peptides