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DNA damage, discoordinated gene expression and cellular senescence in osteoarthritic chondrocytes
Genetic evidence that the human CYP2R1 enzyme is a key vitamin D 25-hydroxylase
Considering that follicles close to the OE lesion tissues exhibit higher total iron levels and lower oocyte retrieval rates than follicles in healthy ovaries [28], iron overload in the OE may impair oocyte maturation and function by affecting granulosa cells close to the lesion and further mediate the release of abnormal exosomes of granulosa cells
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