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The reinforcing effect and DA level induced by DNC + NIC were greater than the sum of the two parts, suggesting that the relationship of the DNC group to nicotine was synergistic rather than additive, and the synergistic effect was further supported by the unique enhancement of the DNC + NIC group in locomotor activity compared to the NIC group (Figure 2C) and anxiety performance (Figure 2D)

Restricting the colour of vapes to a white, black or grey colour with an opaque matt finish and no variance in shade would also help differentiate them from heated tobacco devices, where we are proposing Pantone 448C (drab dark brown)

Concerns about the spread of unregulated e-cigarettes were believed to have led to the removal of the ban

It can be associated with pipe, cigar, or cigarette smoking