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Table of Contents Medications Evidence-based tobacco use treatment is medication assisted treatment.(1) The two medications that give clients the best chance of becoming tobacco free in the long term are Varenicline, also known as Chantix, and combination nicotine replacement therapy (usually a combination of nicotine patches + nicotine gum or lozenge).(2) This is why these two are highlighted in the North Carolina Tobacco Treatment Standard of Care for adults: 100% Tobacco free environments help people quit

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