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The induction of membrane damage and the generation of reactive oxygen species resulted in cell lysis (Shilling et al

[DOI] [PMC free article] [PubMed] [Google Scholar] 36.Yang Y., Wang H., Zhang M., Shi M., Yang C., Ni Q., Wang Q., Li J., Wang X., Zhang C., et al

doi:10.1186/s13024-015-0060-5 pmid:26627850 Cinar B, Mukhopadhyay NK, Meng G, Freeman MR (2007) Phosphoinositide 3-kinase-independent non-genomic signals transit from the androgen receptor to Akt1 in membrane raft microdomains

In vitro results revealed that AFB1 would cause hepatocyte apoptosis via the death receptor pathway and mitochondrial pathway (67)