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In addition to KEAP1, which is the main negative regulator of NRF2 protein stability, many other factors which negatively regulate NRF2 have been discovered and characterized

- The Blood-Brain Barrier Beatriz Achn Buil, PhD candidate in Neuroscience, Institute for Regenerative Medicine (University of Zrich) Did you know that the human brain, though it makes up just 2% of our body weight, accounts for 20% of our energy consumption (Padamsey and Rochefort, 2023)