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demonstrated that BDL-rats treated with edaravone, at a dose of 110 mg/kg/day intraperitoneally for 14 days, show significant improvements in cholestasis-associated hepatic and renal injury, via reduction of ROS levels, lipid peroxidation, protein carbonylation, and GSSG levels

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The co-culture of effector cells and CRC cells was performed in 48-well polystyrene plates at a ratio of 5:1 (effector cells to CRC cells) for 8 h