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The fact that HGF application might represent a viable treatment option for TBI stems from the recent realization that HGF is a potent neurotrophic factor in many brain regions (Kato et al., 2009

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Schwartz GG, Steg PG, Szarek M, Bhatt DL, Bittner VA, Diaz R, Edelberg JM, Goodman SG, Hanotin C, Harrington RA, Jukema JW, Lecorps G, Mahaffey KW, Moryusef A, Pordy R, Quintero K, Roe MT, Sasiela WJ, Tamby JF, Tricoci P, White HD, Zeiher AM, Committees OO

When NAC was given alone, it accelerated senescence and shortened the lifespan of the nematode worm Caenorhabditis elegans [27]