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It exists in both its reduced state (GSH) as well as an oxidized state (GSSG), and the relative amounts of each determine the redox status of a cell ( Fig

Inhibition of DNA Repair Increases Melphalan Efficacy DHA: dehydroascorbic acid, H2O2: hydrogen peroxide, GSH: glutathione, GSSG: glutathione disulfide General Oncology sponsored the nearly complete phase 1 SHARON trial, which is evaluating the safety of GO-4 in patients with BRCA-mutated Stage IV pancreatic cancer and stage IV breast cancer

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