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55 Together, the combined actions of various disorders in the proximal signaling components leads to impaired glucose metabolism and IR, and a major challenge remains for understanding IR mechanisms regarding how to distinguish the causes from insulin effects or primary defects from their consequences

5.1.2.1 Coenzyme Q10 The respiratory transport chain depends on Coenzyme Q10 (CoQ10), a fat-soluble substance found in the membranes of practically all human tissues

S-nitrosylated human alpha (1)-protease inhibitor

A pituitary-specific knockout of Foxo1 causes a delay in the terminal differentiation of somatotrophs but does not affect commitment of pituitary progenitor cells to the somatotroph lineage (269)