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In other embodiments of the invention, Alzheimer's disease may be excluded from this definition

12,40 Clinical safety and efficacy evaluations were conducted over a 6-month follow-up period (180 14 days)

Figure 5 4.4 Direct TAM cancer cell ferroptosis interactions: a mechanistic narrative Tumor-associated macrophages (TAMs) orchestrate ferroptotic sensitivity in cancer cells through a set of tightly interlinked metabolic and immunological interactions ( Bidirectional signaling further reinforces this crosstalk: tumor-cellderived lactate, HMGB1, prostaglandins, and oxidized lipids polarize macrophages toward either ferroptosis-promoting (M1-like) or ferroptosis-restraining (M2-like) states

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