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doi: 10.1016/j.cell.2012.03.042 23

In the methionine cycle, homocysteine is turned into methionine with the help of an enzyme called betaine homocysteine methyltransferase (BHMT)

These findings indicated that the combination of (-)-Vestitol and Salviolone had synergistic effects on reducing both the A plaque burden and toxic soluble A levels in the cortex and hippocampus of APP/PS1 transgenic mice