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Clinical trials show 1522% average body weight reduction over 68 weeks results that diet and exercise alone rarely produce for patients whove already been consistent with both

The integration of metagenomics, metabolomics, and host immunologic and metabolic profilingapproaches that have been increasingly highlighted in human probiotic trials and precision nutrition studies conducted between 2023 and 2025 will be pivotal in understanding the mechanisms that distinguish responders from non-responders and in developing validated predictive biomarkers to inform personalized probiotic selection (581)

Vorburger SA, Gu J, Fang B, Pataer A, Yoshida K, Liu Y, Feig B, Swisher SG , Hunt KK

18 , e1009882 (2022)