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DMSA is considered the preferred treatment for organic mercury poisoning due to its ability to reduce the brain tissue burden of methylmercury indirectly by altering the brainblood equilibrium, despite the fact that DMSA by itself is unable to pass through the bloodbrain barrier

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Although studies in women with endometriosis treated with metformin are scarce, it has been demonstrated that metformin may avoid the main side-effects of other treatments and exert anti-inflammatory, anti-proliferative, antioxidative, and anti-angiogenic effects on endometriosis, suggesting its potential role in the management of endometriosis (Figure 2)

They describe how the blend has been documented in practice, not a prescribed regimen