The biosynthesis of oxalates in the liver accounts for 50-80% of the bodys oxalate pool
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Contributing factors may include female age, anatomical and chromosomal irregularities, genetic predispositions, endocrinological issues, placental abnormalities, infections, lifestyle choices such as smoking and alcohol use, psychological influences, and exposure to environmental hazards like heavy metals, pollution, and radiation ( Despite ongoing research, the underlying causes of RM remain elusive, hindering effective treatment options and adding to the emotional burden on patients
Patients with a history of diabetic retinopathy should have appropriate eye examinations before initiating therapy and regularly thereafter