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It works synergistically with the cytochrome P450 system, which is responsible for metabolizing drugs and other substances through "Phase I" (e.g., oxidation and reduction reactions), imparting certain polarity and reactivity

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Glycyrrhizin shows significant reduction in the degree of ferroptosis and inhibits OxS and provides anti-ferroptotic liver protection through up-regulation of Nrf2, HO-1 and Gpx4

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