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However, you should: Call 999 or go to A&E immediately if you experience signs of a severe allergic reaction (difficulty breathing, severe throat/facial swelling, or collapse) Contact your GP if you experience a rash, itching, persistent pain at the injection site, or worsening neurological symptoms despite treatment If you suspect any side effects from your B12 injections, you can report them through the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk)

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Both semaglutide and liraglutide are MHRA-approved and are supported by NICE technology appraisals TA875 for semaglutide and TA664 for liraglutide which set out specific eligibility criteria