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Results We identified 46 peer-reviewed papers with a total of 22,939 COVID-19 patients, 5421 (23.6%) experienced disease progression and 2914 (12.7%) with a history of smoking (current and former smokers)

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nAChRs are a heterogeneous family of ion channels, that are expressed on various cellular regions of both excitatory and inhibitory neurons, allowing for modulation of neurotransmitters (45, 46)

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