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For example, in an energy-restricted IF intervention using a modified fasting regimen of 5:2 (5 days normal feeding:2 days fasting), 12 weeks of energy restriction elicited approximately a 5% reduction in weight ( Differential abundance analysis revealed increases in several genera, including Incertae sedis and Eubacterium fissicatena group , and a decrease in Sellimonas in IF1-P