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In total, 91% of current, former, and experimental smokers (see Table 2 for a summary of the four smoking status categories) smoked their first whole cigarette before age 21

CS-induced oxidative stress is responsible for altered cellular metabolism, including increased infiltrating immune cells, pro-inflammatory cytokine production, proteaseantiprotease imbalance, lipid peroxidation, apoptosis, upregulation of unfolded protein response (UPR), and protein misfolding

Prospective study of cigarette smoking and the risk of primary open-angle glaucoma