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Indeed, some current work shows that treatment with chemical activators of the Nrf2-ARE pathway prior to the toxic insults can reduce cellular damage in the Nrf2 wildtype mice but not the Nrf2 KO 26 , 27 , 28 , 31 , 32

In addition, fasting blood glucose and HOMA-IR were greatly improved (p 0.05), indicating enhanced insulin sensitivity compared with the glibenclamide or control group suggesting the potential hypoglycemic and insulin-sensitizing properties of Spirulina sp

Qin W, Yang J, Ni Y, Deng C, Ruan Q, Ruan J, et al