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however, only variable efficacy has been demonstrated in reducing disease activity in SLE patients, possibly due to trial design that cannot preselect those patients that might benefit the most from peptide immunotherapy

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Tirzepatide (Compounded): A dual GLP-1/GIP receptor agonist that regulates appetite, improves metabolic function, and enhances fat loss

This mechanism underlies the interest in GHRH-based peptides for visceral fat reductiona topic explored in clinical trials with Tesamorelin, which has FDA approval for HIV-associated lipodystrophy