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Oral submucous fibrosis OSF is a chronic, insidious disease that affects the submucosa of the oral cavity resulting in progressive limitation of mouth opening which is a hallmark feature of this disease18

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A 2022 systematic review and meta-analysis that reviewed data from approximately 5.5 million women corroborated these findings, concluding that cannabis use increased the risk of low birth weight, preterm birth and smallness for gestational age, independent of the effects of other drugs or tobacco