Specifically, it has been reported that H 2 O 2 -dependent inactivation of autophagy-related gene-4 ( ATG4 ) increases LC3-associated autophagosomes and that ATM-mediated oxidation of AMP-activated protein kinase (AMPK) inhibits mammalian target of rapamycin 1 (TORC1), a pivotal negative regulator of autophagy 115,116,117 (Fig
The red transcript variants do not codify for any isoform
Typically, human NK cells are identified by the presence of CD56 proteins and the absence of CD3 proteins on their surface, and can be further subcategorized based on the relative expression of surface marker proteins CD56 and CD16, primarily into CD56 dim and CD56 bright subsets (111)
Chambers RC, Leoni P, Kaminski N, Laurent GJ, Heller RA: Global expression profiling of fibroblast responses to transforming growth factor-beta1 reveals the induction of inhibitor of differentiation-1 and provides evidence of smooth muscle cell phenotypic switching