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Outline how oxidative glucose metabolism and the pentose phosphate pathway are regulated to balance energy needs and NADPH production MODES OF OPERATION OF THE PATHWAY The pentose phosphate pathway can operate in several modes, depending on the needs of the cell

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ROS generates around 10,000 modifications in the DNA bases, resulting in dsDNA/ssDNA breaks, DNA intrastrand adducts, and cross-links to other molecules [40]

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