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There have been some reports of pulmonary aspiration (a complication where food from your stomach is inhaled into your lungs) while under general anesthesia or deep sedation in people taking tirzepatide, likely due to delayed stomach emptying

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10.1080/10408398.2024.2357701 [DOI] [PubMed] [Google Scholar] 62.Hamsalakshmi AAM, Arehally MM, Joghee S, Chidambaram SB

Pharmacokinetic Profile Route of Administration Intravenous Dosing Frequency Once daily Route of Administration : used in animal studies as topical, intradermal, intra-articular, or intravenous applications Dosing Frequency : Once daily Half-Life : Varies depending on experimental design