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[DOI] [PubMed] [Google Scholar] 3.Poole R., Kennedy O.J., Roderick P., Fallowfield J.A., Hayes P.C., Parkes J

The typical MichaelisMenten curves were obtained by plotting the corresponding initial reaction rates and substrate concentrations (Fig

Unadjusted p-values are derived from the two-sided Wilcoxon rank-sum test

In line with these previous results, TAC-induced cardiac samples exhibited elevated MDA and Fe 2+ levels together with higher levels of ROS production, mitochondrial phenotypes consistent with ferroptosis including decreased cristae and a smaller volume, and reductions in the expression of GPX4, GSH, FSP1, and CoQ10