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This suggests that estrogen may confer protective effects on the upper airway by inhibiting CIH-induced HIF-1 expression (17, 28, 68), with ER mediating this effect (17)

Expert Opin Ther Pat 28:197210 Cioffi CL, Wolf MA, Guzzo PR, Sadalapure K, Parthasarathy V, Dethe D, Maeng J-H, Carulli E, Loong DT, Fang X (2013) Design, synthesis, and SAR of N-((1-(4-(propylsulfonyl) piperazin-1-yl) cycloalkyl) methyl) benzamide inhibitors of glycine transporter-1

Cagrilintide Cagrilintide is an investigational amylin receptor agonist developed for the treatment of obesity and weight management