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690 Bioinformatics analysis and qPCR results of rat spinal cord tissue showed that mRNA levels of PTGS2, JUN, RELA, ATF3, TLR4, HMOX1, and STAT3 were upregulated, while mRNA levels of MAPK9, MAPK1, and VEGFA were downregulated

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Efpeglenatide is a drug in which an exendin-4 analog is linked to a human immunoglobulin G4 fragment through a polyethylene glycol (PEG linker), allowing for Fc receptor of neonate (FcRn)-mediated recycling and reduced excretion through the kidneys [50]