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Artesunate Studies (114, 115) have found that the antimalarial drug artemisinin analog artesunate (ARS) has strong immunosuppressive activity in RA model, which can inhibit the formation of germinal centers, B cell proliferation and the production of autoantibodies, increase Foxp3 expression, reduce the formation of pannus, and cartilage and bone erosion

Their presence (or sudden absence) provides indirect evidence about whether the medication is working at full strength

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Posteriormente los pacientes fueron tratados con carbidopa-levodopa