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These include: Endogenous reactive metabolites such as products arising from oxidative metabolism of lipids, nucleic acids and catecholamines Xenobiotics which are not normally found in the body and can include naturally occurring compounds or they can be man made in origin such as drugs or environmental pollutants Heavy metals such as mercury, lead, cadmium and arsenic The chemical reactivity of many of these compounds cause interference with the normal biological processes and hence they are toxic

[Epub ahead of print] The Safety and Efficacy of LowDose Naltrexone in the Management of Chronic Pain and Inflammation in Multiple Sclerosis, Fibromyalgia, Crohns Disease, and Other Chronic Pain Disorders

Increased IL-1 expression and amylase activity in caerulein-triggered pancreatitis [87]

Maybe thats going to bias me now because I agreed with a lot of it